Neuroscience in Denmark

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General information

Name (center, department, group or other)
Copenhagen CSF Study Group, The Neuroscience Centre Rigshospitalet and Copenhagen University
Contact name
Marianne Juhler
Contact email
Contact title
26. June 2015
(Last edited: 5. March 2017)

Brief description of research activities

1. Physiology of intracranial pressure (ICP) regulation; particularly the influence of posture and gravity on ICP; CSF circulation research and ICP measurement bio-technology. My research covers experimental and clinical research methods. The main clinical focus is on hydrocephalus and related disorders in both childrem and adults. The research acitivities are coordinated and gathered in the multidisciplinary Copenhagen CSF Study Group. External collaboration includes Danish Technical University (DTU Electro), Århus University and Cambridge Neuroscience.
Keywords: ICP, hydrocephalus
2. Clinical pediatric neurosurgery; particularly Crebellear Mutism Syndrome


ICP, ICP telemetry, CSF physiology, hydrocephalus, pediatric hydrocephalus, cerebellar mutism

Research tools and techniques

Experimental ICP measurement
Experimental models
Human ICP measurement and regulatory studies
Prdiatric neursurgery multicentre trials

Scientific Personnel

No of Associate Professors/Postdocs: 1
No of PhD students: 5
Other: 9

Key references from within the last 5 years

1: Kofoed Månsson P, Johansson S, Ziebell M, Juhler M. Forty years of shunt
surgery at Rigshospitalet, Denmark: a retrospective study comparing past and
present rates and causes of revision and infection. BMJ Open. 2017 Jan
16;7(1):e013389. doi: 10.1136/bmjopen-2016-013389. PubMed PMID: 28093434; PubMed
Central PMCID: PMC5253591.

2: Andresen M, Hadi A, Juhler M. Evaluation of Intracranial Pressure in Different
Body Postures and Disease Entities. Acta Neurochir Suppl. 2016;122:45-7. doi:
10.1007/978-3-319-22533-3_9. PubMed PMID: 27165875.

3: Gudrunardottir T, Morgan AT, Lux AL, Walker DA, Walsh KS, Wells EM, Wisoff JH,
Juhler M, Schmahmann JD, Keating RF, Catsman-Berrevoets C; Iceland Delphi Group..
Consensus paper on post-operative pediatric cerebellar mutism syndrome: the
Iceland Delphi results. Childs Nerv Syst. 2016 Jul;32(7):1195-203. doi:
10.1007/s00381-016-3093-3. Review. PubMed PMID: 27142103.

4: Petersen LG, Petersen JC, Andresen M, Secher NH, Juhler M. Postural influence
on intracranial and cerebral perfusion pressure in ambulatory neurosurgical
patients. Am J Physiol Regul Integr Comp Physiol. 2016 Jan 1;310(1):R100-4. doi:
10.1152/ajpregu.00302.2015. PubMed PMID: 26468260.

5: Andresen M, Hadi A, Petersen LG, Juhler M. Effect of postural changes on ICP
in healthy and ill subjects. Acta Neurochir (Wien). 2015 Jan;157(1):109-13. doi:
10.1007/s00701-014-2250-2. PubMed PMID: 25307778.

6: Lilja A, Andresen M, Hadi A, Christoffersen D, Juhler M. Clinical experience
with telemetric intracranial pressure monitoring in a Danish neurosurgical
center. Clin Neurol Neurosurg. 2014 May;120:36-40. doi:
10.1016/j.clineuro.2014.02.010. PubMed PMID: 24731573.

7: Gudrunardottir T, Sehested A, Juhler M, Schmiegelow K. Fronto-cerebellar fiber
tractography in pediatric patients following posterior fossa tumor surgery.
Childs Nerv Syst. 2013 May;29(5):715-6. doi: 10.1007/s00381-013-2070-3. PubMed
PMID: 23508349.

8: Andresen M, Juhler M. Intracranial pressure following complete removal of a
small demarcated brain tumor: a model for normal intracranial pressure in humans.
J Neurosurg. 2014 Oct;121(4):797-801. doi: 10.3171/2014.2.JNS132209. PubMed PMID:

Scherfigsvej 7
2100 Copenhagen Ø
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